WiththeheadsoftheAgencyandthePortMafiaonthebrinkofdeathduetoa“cannibal“virus,theviciousrivalrybetweenthegroupsrearsitsheadoncemore!AsthefearsomeAkutagawaandformerassassinKyoukafaceoffinafatalbattle,arareconfrontationbetweenthecockyChuuyaandgeniusdetectiveRanpothreatenstodisruptthecity’speace.Meanwhile,KunikidaandAtsushiareofftosearchforacure,butwilltheymakeitintimeorwilltheybedoomedtofallbeforetheiroldnemeses?